Zithrin 500 is a potent macrolide antibiotic containing Azithromycin Dihydrate. It is widely used to treat various bacterial infections by inhibiting the synthesis of essential bacterial proteins, thereby stopping their growth. Produced by Renata PLC (formerly Renata Limited), it is a cornerstone of antibiotic therapy in Bangladesh due to its convenient once-daily dosing and high tissue penetration.
What is Zithrin 500 Used For?
Zithrin 500 mg is prescribed for a variety of infections caused by susceptible organisms:
-
Respiratory Tract Infections: Including sinusitis, pharyngitis, tonsillitis, acute bronchitis, and community-acquired pneumonia.
-
Skin and Soft Tissue Infections: Treatment of uncomplicated skin infections caused by Staphylococcus aureus or Streptococcus pyogenes.
-
Sexually Transmitted Diseases (STDs): Specifically non-gonococcal urethritis and cervicitis caused by Chlamydia trachomatis.
-
Ear Infections: Management of acute otitis media in children and adults.
-
Typhoid Fever: Often used as a highly effective treatment for enteric fever.
Key Reminder: Zithrin is an antibiotic and is not effective against viral infections like the common cold or flu. For a deeper look at the clinical efficacy of this molecule, you can review the pharmacology and clinical applications of Azithromycin on DrugBank.
Dosage
For adults and adolescents 15 years and older:
-
Standard 3-Day Course: One 500 mg tablet once daily for 3 days.
-
Standard 5-Day Course: 500 mg on Day 1, followed by 250 mg once daily on Days 2 through 5.
-
Chlamydia (STD): A single 1 gram (1000 mg) dose (two 500 mg tablets taken at once).
-
Timing: Zithrin tablets can be taken with or without food. However, taking it with food may reduce potential stomach upset.
Common Side Effects
Zithrin 500 is generally well-tolerated, but common side effects may include:
-
Diarrhea or loose stools
-
Nausea and vomiting
-
Abdominal pain or cramping
-
Headache or dizziness
-
Fatigue
Important 2026 Safety Update: Global health authorities maintain a warning regarding QT prolongation (a rare heart rhythm problem) associated with macrolides. A 2025 meta-analysis published in the Lancet Infectious Diseases noted that the risk is extremely low but higher in elderly patients or those with existing heart conditions. If you experience fainting or a fast, pounding heartbeat, contact a doctor immediately.
Important Warnings & Precautions
-
Antacid Interaction: Do not take antacids containing aluminum or magnesium within 2 hours before or after taking Zithrin, as they can reduce its absorption.
-
Liver Health: Use with caution in patients with pre-existing liver disease; stop use if jaundice (yellowing of skin/eyes) occurs.
-
Allergic Reactions: Stop taking the medicine immediately if you develop an itchy rash, swelling of the face, or breathing difficulties.
-
Pregnancy/Lactation: Generally considered safe when clearly needed, but consult your physician as Azithromycin is excreted in breast milk.
Zithrin 500 vs. Zimax 500: Key Differences and Usage
Both are leading brands of Azithromycin in Bangladesh, manufactured by top-tier companies.
| Feature | Zithrin 500 (Renata) | Zimax 500 (Square) |
| Active Ingredient | Azithromycin (500 mg) | Azithromycin (500 mg) |
| Manufacturer | Renata PLC | Square Pharmaceuticals PLC |
| Action | Bacteriostatic (Stops growth) | Bacteriostatic (Stops growth) |
| Standard Pack | 15 Tablets (3×5 Strip) | 10 Tablets (1×10 Strip) |
| Unit Price | ৳40.00 | ৳40.00 |
Zithrin Price (January 2026 Update)
Pricing for the Zithrin range by Renata PLC as of January 2026.
| Product Name | Strength | Format | Unit Price (BDT) |
| Zithrin 500 | 500 mg | Tablet | ৳40.00 |
| Zithrin 250 | 250 mg | Tablet/Capsule | ৳25.00 |
| Zithrin Suspension | 200 mg/5 ml | 15 ml Bottle | ৳95.00 |
| Zithrin Suspension | 200 mg/5 ml | 35 ml Bottle | ৳140.00 |
| Zithrin Suspension | 200 mg/5 ml | 50 ml Bottle | ৳200.00 |
| Zithrin Injection | 500 mg | IV Infusion Vial | ৳460.00 |
Zithrin 500 Alternative Brands & Prices
If you are looking for an alternative Azithromycin 500 mg brand in Bangladesh as of January 2026:
| Brand Name | Company Name | Price per Unit (BDT) |
| Zimax 500 | Square Pharmaceuticals | ৳40.00 |
| Azithrocin 500 | Beximco Pharmaceuticals | ৳35.00 |
| Tridosil 500 | Incepta Pharmaceuticals | ৳35.00 |
| Zithrox 500 | Eskayef (SK+F) | ৳40.00 |
| Azin 500 | ACME Laboratories Ltd. | ৳55.00 |
| Rozith 500 | Healthcare Pharmaceuticals | ৳50.00 |
| AZ 500 | Aristopharma Ltd. | ৳55.00 |
| Azicin 500 | Opsonin Pharma Ltd. | ৳45.00 |
| Romycin 500 | Ibn Sina Pharmaceuticals | ৳40.00 |
| Odazyth 500 | ACI Limited | ৳40.00 |
Frequently Asked Questions (FAQ)
Q: What is the Zithrin 500 mg price in Bangladesh?
As of January 2026, the retail price for a 500 mg Zithrin tablet is ৳40.00. A strip of 5 tablets typically costs ৳200.00.
Q: What are the Zithrin 500 side effects?
The most common side effects are diarrhea, nausea, abdominal pain, and headache. These are generally mild and disappear after the course is completed.
Q: What is Zithrin 500 used for?
It is a broad-spectrum antibiotic used for respiratory tract infections, ear infections, skin infections, and certain sexually transmitted diseases.
Q: What is the recommended Zithrin 500 dose?
For most common infections, the dose is one 500 mg tablet once daily for 3 to 5 days. For Chlamydia, a single 1000 mg dose is often used.
Q: Is Zithrin 500 good for a cough?
It is only effective if the cough is caused by a bacterial infection like pneumonia or bacterial bronchitis. It will not treat a viral cough from the common cold.
Q: What does Zithrin do?
It prevents bacteria from producing the proteins they need to grow and multiply, which allows your body’s immune system to clear the infection.
Q: Does Zithrin 500 make you sleepy?
Drowsiness is not a common side effect of Zithrin, but some users may experience mild dizziness.
Q: Is Azithromycin (Zithrin) high risk?
It is generally safe but carries a rare risk of heart rhythm issues (QT prolongation) and liver problems. It should only be taken as prescribed to prevent antibiotic resistance.
Q: Is Zithrin 500 safe during pregnancy?
It is generally considered safe during pregnancy (Category B) but should be used only when prescribed by a doctor.
Disclaimer: This is educational information only (updated January 2026). Not a substitute for professional medical advice. Always
