Prosma Syrup is an oral formulation containing Ketotifen Fumarate, a potent anti-allergic agent with mast-cell stabilizing and antihistamine properties. It is specifically used for the long-term prevention of bronchial asthma and the symptomatic relief of various allergic disorders. Produced by ACI Limited, it is widely recognized for its efficacy in reducing the frequency and severity of asthma attacks over time.
What is Prosma Syrup Used For?
Prosma Syrup (1 mg/5 ml) is primarily prescribed for:
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Asthma Prophylaxis: Long-term prevention of all forms of bronchial asthma.
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Allergic Rhinitis: Relief from seasonal and perennial hay fever symptoms.
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Allergic Conjunctivitis: Treatment of eye-related allergy symptoms.
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Skin Allergies: Management of urticaria (hives) and other multi-system allergic reactions.
Clinical Insight: Prosma works by stabilizing mast cells and inhibiting the release of inflammatory mediators like histamine. It is important to note that Prosma is not a bronchodilator and will not stop an asthma attack that has already started. Clinical research suggests its full protective effect may take several weeks to develop. For a detailed molecular analysis, you can view Ketotifen’s pharmacology on DrugBank.
Dosage
Dosage should be strictly followed as directed by a physician. Prosma Syrup is typically taken twice daily with food.
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Adults: 5 ml (1 mg) twice daily. In severe cases, the dose may be increased to 10 ml twice daily.
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Children (Above 3 years): 5 ml (1 mg) twice daily.
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Infants (6 months to 3 years): 0.05 mg (0.25 ml syrup) per kg of body weight twice daily.
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Sensitive Patients: For those prone to sedation, a starting dose of 0.5 mg to 1 mg at night is often recommended for the first few days.
Common Side Effects
While usually well-tolerated, initial side effects may include:
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Drowsiness or sedation
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Dry mouth
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Mild dizziness
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Hyperactivity or irritability (especially in children)
2026 Safety Update: According to recent reviews in respiratory health journals, the sedative effect of Ketotifen usually disappears spontaneously after a few days of consistent use. Patients are advised to monitor for any unusual sleep disturbances or mood changes.
Important Warnings & Precautions
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Transition Period: Do not suddenly stop other anti-asthmatic treatments (especially steroids) when starting Prosma; continue them for at least 2 weeks.
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Interactions: Avoid concurrent use with oral antidiabetic agents, as a reversible fall in platelet count has been reported.
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Alcohol & Sedatives: Prosma may enhance the effects of alcohol, hypnotics, and other antihistamines.
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Machine Operation: Avoid driving or operating machinery during the first few days until your response to the medication is known.
Prosma Syrup vs. Alatrol Syrup: Key Differences and Usage
Prosma is primarily used as a long-term preventive measure for asthma, whereas Alatrol (Cetirizine) is a fast-acting antihistamine used for immediate relief of allergy symptoms.
| Feature | Prosma Syrup (Ketotifen) | Alatrol Syrup (Cetirizine) |
| Drug Class | Mast Cell Stabilizer / H1 Blocker | 2nd Gen Antihistamine |
| Primary Use | Asthma Prevention & Chronic Allergy | Acute Allergy & Hay Fever |
| Action Speed | Slow (takes weeks for full effect) | Fast (works within 1–3 hours) |
| Sedation | Mild to Moderate | Low / Minimal |
| Unit Price (100ml) | ৳76.00 | ৳50.00 – ৳60.00 |
Prosma Syrup Price in Bangladesh (January 2026 Update)
The following table reflects the current retail pricing for ACI Limited’s Prosma range.
| Product Name | Format | Strength | Price (BDT) |
| Prosma Syrup | Syrup | 1 mg/5 ml (100 ml) | ৳76.00 |
| Prosma Tablet | Tablet | 1 mg | ৳4.00 (Per Unit) |
Prosma Syrup Alternative Brands & Prices
If you are looking for an alternative to Prosma 100ml syrup, here are the top 10 brands available in Bangladesh as of January 2026:
| Brand Name | Company Name | Price (100ml BDT) |
| Ketifen | ACME Laboratories Ltd. | ৳75.00 |
| Tofen | Beximco Pharmaceuticals | ৳75.00 |
| Tosma | Square Pharmaceuticals | ৳76.00 |
| Zadit | Incepta Pharmaceuticals | ৳75.00 |
| Orotifen | General Pharmaceuticals | ৳75.00 |
| Stafen | Aristopharma Ltd. | ৳75.00 |
| Toti | Eskayef (SK+F) | ৳62.00 |
| Ketof | Ibn Sina Pharmaceuticals | ৳66.00 |
| Kofen | Opsonin Pharma | ৳55.00 |
| Kiti | Beacon Pharmaceuticals | ৳75.00 |
Frequently Asked Questions (FAQ) About Prosma Syrup
Q: What is the Prosma Syrup price in Bangladesh?
As of January 2026, the retail price for a 100 ml bottle of Prosma Syrup is ৳76.00.
Q: What is Prosma Syrup used for?
It is used for the long-term prevention (prophylaxis) of bronchial asthma and for treating symptoms of allergic rhinitis, conjunctivitis, and hives.
Q: What are the Prosma Syrup side effects?
Common initial side effects include drowsiness, dry mouth, and slight dizziness. Some children may experience irritability or hyperactivity.
Q: Is Prosma Syrup safe during pregnancy?
Although no teratogenic effects have been proven, it is generally not recommended during pregnancy or lactation unless specifically advised by a doctor. You can review safety profiles on PubMed.
Q: What is the recommended Prosma dose?
For adults and children over 3, the standard dose is 5 ml (1 mg) twice daily with food.
Q: Does Prosma Syrup make you sleepy?
Yes, drowsiness is common at the start of treatment but usually resolves within a few days.
Q: Can Prosma treat an ongoing asthma attack?
No. Prosma is a preventive medication. You must use a rescue inhaler (like Salbutamol) for sudden breathing difficulties.
Q: Is it safe to take Prosma with diabetes medicine?
Caution is required. Combining Ketotifen with oral antidiabetic drugs can occasionally cause a temporary drop in platelet count. Consult your doctor.
Q: Are there alternatives to Prosma in Bangladesh?
Yes, popular alternatives include Ketifen (ACME), Tofen (Beximco), and Tosma (Square), most priced similarly around ৳75.00.
Disclaimer: This information is for educational purposes as of January 2026. Always consult a qualified physician before starting any medication, especially for children or patients with pre-existing conditions.
