Melphin (Oral Suspension) is a highly effective anthelmintic (anti-worm) medication containing Pyrantel Pamoate. It is widely used to treat intestinal parasite infestations in both adults and children. It works as a neuromuscular blocking agent that paralyzes worms, causing them to lose their grip on the intestinal wall so they can be passed out of the system naturally. Produced by Beximco Pharmaceuticals Ltd., this guide provides updated information for early 2026.
What is Melphin Syrup Used For?
Melphin 50 mg/ml suspension is specifically indicated for the treatment of:
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Ascariasis: Infections caused by Ascaris lumbricoides (large roundworms).
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Enterobiasis: Infections caused by Enterobius vermicularis (pinworms or threadworms).
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Hookworm Infections: Treatment of Ancylostoma duodenale and Necator americanus.
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Trichostrongyliasis: Infections caused by Trichostrongylus species.
Critical Safety Note: Melphin paralyzes live worms to expel them. In cases of very heavy worm loads, medical supervision is advised to prevent intestinal obstruction. For technical details, you can review Pyrantel on DrugBank.
Dosage
Dosage is based on body weight and should be administered as a single dose:
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Standard Dose: 11 mg/kg body weight as a single oral dose.
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Maximum Dose: The total dose should not exceed 1 gram (20 ml of suspension).
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Pinworm Treatment: It is often recommended to repeat the dose once after 2 weeks to prevent reinfection.
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Administration: Can be taken at any time of day, with or without food. No fasting or purging is required before or after the dose.
Common Side Effects
Melphin is generally well-tolerated at recommended doses, but some patients may experience:
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Nausea, vomiting, or abdominal cramps.
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Diarrhea or loss of appetite (anorexia).
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Headache or dizziness.
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Drowsiness or insomnia.
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Mild skin rash.
Important Warnings & Precautions
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Piperazine Interaction: Do not take Melphin with Piperazine, as they act against each other (antagonistic).
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Liver Function: Use with extreme caution in patients with pre-existing liver dysfunction.
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Pregnancy: Usually contraindicated in pregnant women as sufficient human studies are lacking. Use only if strictly necessary under a doctor’s guidance.
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Children: Not recommended for children under 1 year of age.
Melphin vs. Solas: Key Differences
While both treat worms, they belong to different chemical classes and have different spectrums of activity.
| Feature | Melphin (Pyrantel) | Solas (Mebendazole) |
| Action | Paralyzes the worms | Starves the worms of glucose |
| Primary Use | Roundworm, Pinworm, Hookworm | Broad spectrum (includes Whipworm) |
| Dosage | Single weight-based dose | Often 2 doses/day for 3 days |
| Whipworm Effect | Ineffective | Effective |
| Unit Price | ৳16.10 (10ml) | ৳18.00 – ৳22.00 |
Melphin Syrup Price (February 2026 Update)
The following retail prices are current for Melphin variants produced by Beximco Pharmaceuticals Ltd.
| Product Name | Strength | Unit Price (BDT) | Pack Size |
| Melphin Suspension | 50 mg / ml | ৳16.10 | 10 ml Bottle |
| Melphin Tablet | 125 mg | ৳1.66 | 10 Tablets (Strip) |
| Melphin (12’s Box) | 50 mg / ml | ৳193.22 | 12 x 10 ml Bottles |
Melphin Syrup Alternative Brands & Prices
While Pyrantel Pamoate is a niche generic, it is available from several trusted manufacturers. Below are the top available alternatives in 2026.
| Brand Name | Company Name | Generic Ingredient | Price (BDT) |
| Delentin | Renata PLC | Pyrantel Pamoate | ৳16.05 (10ml) |
| Wormex | Hallmark Pharma | Pyrantel Pamoate | ৳11.07 (10ml) |
| Almex | Square Pharma | Albendazole (Substitute) | ৳21.85 (10ml) |
| Solas | Square Pharma | Mebendazole (Substitute) | ৳20.00 (10ml) |
| Sintel | ACI Limited | Albendazole (Substitute) | ৳19.05 (10ml) |
| Alben | Incepta Pharma | Albendazole (Substitute) | ৳20.00 (10ml) |
| Worm Nil | Opsonin Pharma | Mebendazole (Substitute) | ৳18.00 (10ml) |
| Zentel | GSK (Imported) | Albendazole (Substitute) | ৳30.00+ (10ml) |
| Ben-A | Aristopharma Ltd. | Albendazole (Substitute) | ৳20.00 (10ml) |
| G-Pyrantel | Gonoshasthaya | Pyrantel Pamoate | ৳1.20 (Tablet) |
Frequently Asked Questions (FAQ) About Melphin Syrup
Q: What is the Melphin Syrup price in Bangladesh?
As of February 2026, the retail price for a 10 ml bottle of Melphin Suspension is ৳16.10.
Q: What is Melphin Syrup used for?
It is used to treat infections caused by intestinal worms, specifically roundworms, pinworms (threadworms), and hookworms.
Q: What are the common Melphin Syrup side effects?
Common side effects include nausea, stomach cramps, headache, and dizziness. It is generally much milder than older deworming medications.
Q: Is Melphin Syrup safe during pregnancy?
No, Melphin is generally avoided during pregnancy unless specifically prescribed by a doctor after weighing the risks.
Q: Do I need to fast before taking Melphin?
No, you do not need to fast or take a laxative. It can be taken with or without food at any time of the day.
Q: Can Melphin be given to a 6-month-old baby?
No, Melphin is not recommended for children under 1 year of age. For children between 1 and 2 years, use only if directed by a pediatrician.
Q: Does Melphin kill the worm eggs?
No, it only kills the adult worms. This is why a second dose after 2 weeks is often necessary for pinworms, to kill any worms that hatched from eggs after the first treatment.
Q: Why shouldn’t I take Melphin with Piperazine?
They are antagonistic, meaning they cancel each other out. If taken together, neither medication will work effectively to kill the worms.
Q: Will the worms come out alive in the stool?
Because Melphin paralyzes the worms, they are often passed out whole in the stool during a bowel movement.
Disclaimer: This is educational information only (updated February 2026). Not a substitute for professional medical advice. Always consult a qualified physician before starting/stopping any medication.
