Ibuprofen 400 is a potent medication used to reduce fever and treat pain or inflammation caused by many conditions such as arthritis, menstrual cramps, and dental issues. It works by blocking the production of prostaglandins, the chemicals in the body that signal pain and trigger inflammation. Produced by various top-tier manufacturers like ACME Laboratories Ltd. (under the brand Profen), it remains an essential part of the Bangladeshi household medical kit.
What is Ibuprofen 400 Used For?
Ibuprofen 400 mg is formulated for adults and children (usually over 12 years or 40kg) who require effective relief from moderate to severe discomfort. Its primary applications include:
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Pain Relief: Effective for dental pain, backaches, muscular strains, and post-operative recovery.
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Inflammation Control: Treatment of rheumatoid arthritis, osteoarthritis, and gouty arthritis.
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Fever Reduction: Rapidly lowers high body temperatures associated with infections.
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Menstrual Cramps: Relief of primary dysmenorrhea (period pain).
Critical Safety Note: Ibuprofen can cause serious stomach bleeding and kidney issues if used long-term without supervision. For a deeper look at the pharmacological profile of this molecule, you can review the National Library of Medicine (NIH) – Ibuprofen Information.
Dosage
For adults and adolescents weighing over 40 kg, the standard starting dose is one 400 mg tablet three times daily
The tablets should ideally be taken with or immediately after food or a glass of milk to protect the stomach lining. To minimize risks, users should take the lowest effective dose for the shortest duration necessary. The maximum daily dose for adults should generally not exceed 2400 mg (6 tablets) unless directed by a physician.
Common Side Effects
While highly effective, Ibuprofen 400 can cause gastrointestinal and systemic side effects. Research suggests that taking the medication on an empty stomach significantly increases these risks:
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Stomach pain or indigestion
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Nausea and vomiting
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Heartburn or acid reflux
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Dizziness or nervousness
Important Warnings & Precautions
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Avoid with Anticoagulants: Do not take with blood thinners like Warfarin as it significantly increases bleeding risks.
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Kidney Health: Long-term use can lead to kidney impairment; ensure adequate hydration.
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Asthma Sensitivity: Some individuals with asthma may experience worsening symptoms or “aspirin-induced” breathing issues.
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Alcohol: Avoid alcohol consumption while taking Ibuprofen, as it increases the risk of stomach bleeding.
Ibuprofen 400 vs. Paracetamol 500: Key Differences and Usage
Patients often choose between Ibuprofen and Paracetamol (Acetaminophen) for general pain. While both treat pain, their mechanisms and safety profiles differ.
| Feature | Ibuprofen 400 mg | Paracetamol 500 mg |
| Drug Class | NSAID (Anti-inflammatory) | Analgesic & Antipyretic |
| Primary Use | Pain + Swelling/Inflammation | Mild Pain & Fever |
| Action Mechanism | Blocks COX enzymes (Peripheral) | Acts on Central Nervous System |
| Stomach Safety | Can cause ulcers (Take with food) | Generally safe for the stomach |
| Unit Price | ৳1.43 | ৳0.80 – ৳1.20 |
Ibuprofen 400 Price in Bangladesh (January 2026 Update)
Updated pricing for the Ibuprofen range (specifically the Profen brand by ACME) shows stability in the market for 2026.
| Product Name | Strength | Unit Price (BDT) | Strip Price (10 Tablets) |
| Profen 400 | 400 mg | ৳1.43 | ৳14.30 |
| Profen 200 | 200 mg | ৳0.88 | ৳8.80 |
| Profen Susp. | 100mg/5ml | ৳37.00 | 100 ml Bottle |
Ibuprofen 400 Alternative Brands & Prices
If Profen 400 is unavailable, these alternatives from reputable Bangladeshi manufacturers are widely available and priced similarly.
| Brand Name | Company Name | Price per Unit (BDT) |
| Flamex 400 | ACI Limited | ৳1.43 |
| Reumafen 400 | Beximco Pharmaceuticals | ৳1.43 |
| Intaflam 400 | Incepta Pharmaceuticals | ৳1.00 |
| Advel 400 | Opsonin Pharma | ৳1.43 |
| Inflam 400 | Synovia Pharma PLC | ৳1.43 |
| Neurofen 400 | Globe Pharmaceuticals | ৳1.42 |
| Iben 400 | Zenith Pharmaceuticals | ৳1.30 |
| G-Ibuprofen 400 | Gonoshasthaya Pharma | ৳1.20 |
| Arafa 400 | Hudson Pharmaceuticals | ৳1.00 |
| Rebufen 400 | Rephco Pharmaceuticals | ৳1.25 |
Frequently Asked Questions (FAQ) About Ibuprofen 400
1. What is the Ibuprofen 400 mg price in Bangladesh?
As of January 2026, the retail price is approximately ৳1.43 per tablet. A box containing 100 tablets (10 strips) typically costs around ৳143.00.
2. What are the common side effects of Ibuprofen 400?
The most common issues include stomach upset, nausea, heartburn, and mild dizziness. Taking it with food is the best way to prevent gastrointestinal discomfort.
3. What is Ibuprofen 400 used for?
It is used to treat pain and inflammation from conditions like arthritis, dental surgery, menstrual cramps, and common fevers. Unlike paracetamol, it specifically targets swelling.
4. Is Ibuprofen 400 safe during pregnancy?
No, Ibuprofen is generally not recommended during pregnancy, especially after 20 weeks. It can cause kidney problems or heart complications in the fetus. For pain during pregnancy, healthcare providers usually recommend Paracetamol instead.
5. Is Ibuprofen 400 good for a cough?
Ibuprofen does not treat a cough directly. It may help with the body aches or throat inflammation associated with a cold, but it is not a cough suppressant.
6. Does Ibuprofen 400 make you sleepy?
Ibuprofen is not a sedative. However, rare side effects include dizziness. If you feel lightheaded, you should avoid driving until the feeling passes.
7. What is the recommended Ibuprofen 400 dose?
The standard adult dose is one 400 mg tablet every 6 to 8 hours as needed. Never exceed 2400 mg (6 tablets) in a 24-hour period.
8. Is Ibuprofen 400 considered high risk?
It is high risk for individuals with active stomach ulcers, severe heart disease, or late-stage kidney disease. It also increases the risk of gastrointestinal bleeding in the elderly.
9. Are there any alternatives to Ibuprofen 400 in Bangladesh?
Yes, popular alternatives include Flamex 400 (ACI), Reumafen 400 (Beximco), and Intaflam 400 (Incepta). Most are priced at the regulated rate of ৳1.43 per unit.
Disclaimer: This is educational information only (updated January 2026). Not a substitute for professional medical advice. Always consult a qualified physician before starting/stopping any medication.
