Deflux is a prescription medication containing Domperidone (as Domperidone Maleate). It belongs to the class of dopamine antagonists and prokinetics, which work by increasing the movements or contractions of the stomach and intestines. This action facilitates easier food passage and suppresses the “vomiting center” in the brain. Produced by Beximco Pharmaceuticals Ltd., it is a primary treatment for indigestion and nausea in Bangladesh.
What is Deflux Used For?
Deflux 10 mg (Tablets) and Deflux Suspension (Syrup) are prescribed primarily for:
-
Nausea and Vomiting: Relief of symptoms from functional, organic, or infectious origins.
-
Dyspeptic Symptom Complex: Management of bloating, fullness, upper abdominal pain, and belching often associated with delayed gastric emptying.
-
GERD & Reflux: Treatment of gastroesophageal reflux and esophagitis.
-
Parkinson’s Support: Prevention of nausea and vomiting caused by dopamine-agonist medications.
Clinical Insight: Domperidone facilitates gastric emptying and increases lower esophageal sphincter pressure, preventing stomach contents from rising back into the mouth. Recent reviews in the Journal of Gastroenterology highlight its efficacy in diabetic gastroparesis. For a detailed molecular analysis, you may visit the DrugBank entry for Domperidone.
Dosage
Deflux should be taken 15–30 minutes before meals. The dosage varies by age and the condition being treated:
-
Adults (Dyspepsia): 10 mg (1 tablet or 10 ml) taken 3 times daily.
-
Adults (Acute Nausea): 20 mg (2 tablets or 20 ml) every 6–8 hours. (Max: 80 mg/day).
-
Children: 0.2–0.4 mg/kg (approx. 2–4 ml suspension per 10 kg of body weight) every 6–8 hours.
Common Side Effects
Deflux is generally well-tolerated, but some side effects may occur:
-
Dry mouth
-
Headache or dizziness
-
Diarrhea or intestinal cramps
-
Hyperprolactinemia: In rare cases, it may cause breast tenderness or nipple discharge (galactorrhea) due to increased prolactin.
2026 Safety Update: While neurologically safer than older alternatives, doctors warn of rare “extrapyramidal” reactions (uncontrolled movements), particularly in infants whose blood-brain barrier is not fully developed. For broader safety guidelines, refer to the WHO Pharmaceuticals Newsletter.
Important Warnings & Precautions
-
Heart Health: Use with caution in patients with a history of cardiac arrhythmias or prolonged QT intervals.
-
Liver & Kidney: Caution is advised for those with severe hepatic or renal impairment; dose adjustments may be necessary.
-
Gastrointestinal Risk: Do not use if there is evidence of GI bleeding, mechanical obstruction, or perforation.
-
Alcohol: Avoid alcohol as it may increase drowsiness.
Deflux vs. Omeprazole: Key Differences and Usage
While both treat stomach discomfort, Deflux moves food along (prokinetic), while Omeprazole (PPI) reduces the actual acid production.
| Feature | Deflux (Domperidone) | Omeprazole (PPI) |
| Drug Class | Dopamine Antagonist / Prokinetic | Proton Pump Inhibitor |
| Primary Use | Nausea, Bloating, & Vomiting | Acidity, Heartburn, & Ulcers |
| Action | Speeds up stomach emptying | Blocks acid production |
| Timing | 15–30 mins before meals | Usually once daily (Morning) |
| Unit Price | ৳4.00 | ৳5.00 – ৳7.00 |
Deflux Price in Bangladesh (January 2026 Update)
Updated pricing for Beximco’s Deflux range:
| Product Name | Format | Strength | Unit Price (BDT) |
| Deflux 10 | Tablet | 10 mg | ৳4.00 |
| Deflux Meltab | Dispersible Tab | 10 mg | ৳3.50 |
| Deflux Suspension | Syrup | 5 mg/5 ml (100 ml) | ৳50.00 |
| Deflux Drops | Paediatric Drops | 5 mg/ml (15 ml) | ৳20.00 |
Deflux Alternative Brands & Prices
The top 10 alternative brands for Domperidone (10 mg) in Bangladesh as of January 2026:
| Brand Name | Company Name | Price per Unit (BDT) |
| Motigut 10 | Square Pharmaceuticals | ৳4.00 |
| Vomitop 10 | Labaid Pharmaceuticals | ৳4.00 |
| Domydon 10 | Incepta Pharmaceuticals | ৳3.00 |
| Omidon 10 | Incepta Pharmaceuticals | ৳4.00 |
| Domin 10 | ACME Laboratories | ৳4.00 |
| Don-A 10 | Aristopharma Ltd. | ৳4.00 |
| Domstal 10 | Sun Pharmaceutical | ৳2.00 |
| Sandom 10 | Sanofi Bangladesh | ৳2.02 |
| Efodio 10 | Eskayef (SK+F) | ৳4.50 |
| Ridon 10 | Drug International | ৳3.50 |
Frequently Asked Questions (FAQ) About Deflux
Q: What is the Deflux 10 mg price in Bangladesh?
As of January 2026, the retail price for Deflux 10 mg is ৳4.00 per tablet. A 100 ml syrup bottle costs ৳50.00.
Q: What is Deflux used for?
It is primarily used to treat nausea, vomiting, and feelings of fullness or bloating (dyspepsia) by helping the stomach empty faster.
Q: What are the Deflux side effects?
Common side effects include dry mouth, headache, and thirst. In rare cases, it can lead to breast enlargement or milk production due to prolactin changes.
Q: Is Deflux safe during pregnancy?
The safety of Deflux during pregnancy has not been fully established. It is generally not recommended unless the benefit outweighs the risk, especially in the first trimester. Consult a doctor or check MedlinePlus for updates.
Q: What is the recommended Deflux dose?
For adults, 10–20 mg (1-2 tablets) every 6–8 hours is common. It must be taken before meals.
Q: Does Deflux make you sleepy?
Drowsiness is a rare side effect (occurring in less than 1% of patients). Most people do not feel sleepy.
Q: Can Deflux be taken with antacids?
You should not take Deflux at the same time as antacids, as they can lower the absorption of the medicine.
Q: Is Deflux high risk for the heart?
In high doses or for elderly patients, it can affect heart rhythm. Always follow the prescribed dose.
Q: Are there alternatives to Deflux in Bangladesh?
Yes, common alternatives include Motigut, Omidon, and Domin, with prices ranging from ৳2.00 to ৳4.50.
Disclaimer: This information is for educational purposes as of January 2026. Not a substitute for professional medical advice. Always consult a qualified physician before use.
