Brezofil 200 is a prescription medication containing Doxofylline, a new-generation methylxanthine derivative. It is primarily indicated for the maintenance treatment of bronchial asthma and Chronic Obstructive Pulmonary Disease (COPD). Unlike older xanthines, Brezofil is engineered to provide potent bronchodilation with a significantly reduced risk of cardiac and central nervous system side effects. Produced by Incepta Pharmaceuticals Ltd., it remains a frontline choice for respiratory health in 2026.
What is Brezofil 200 Used For?
Brezofil 200 mg is specifically prescribed for:
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Asthma Management: Long-term maintenance to prevent bronchospasms and wheezing.
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COPD Relief: Treatment of chronic bronchitis and emphysema by improving airflow.
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Bronchospasm Prevention: Relief of airway constriction associated with various pulmonary disorders.
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Antitussive Action: Helping to suppress coughs linked specifically to inflammatory lung conditions.
Clinical Insight: Brezofil is a “controller” medication, not a “rescue” inhaler. It is designed to keep airways open over time and should not be used to treat a sudden, acute asthma attack. Recent clinical reviews suggest that Doxofylline’s unique structure results in fewer interactions with adenosine receptors compared to theophylline. For a deeper molecular analysis, you can review Doxofylline on DrugBank.
Dosage
Dosage must be individualized based on the patient’s response and age. It is typically taken two to three times daily.
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Adults: Usually 200 mg to 400 mg, two or three times daily.
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Children (>12 years): One 200 mg tablet, two or three times daily.
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Elderly: Dosage may need reduction (200 mg twice daily) in patients with liver or heart complications.
Common Side Effects
Brezofil is generally well-tolerated, but similar to caffeine-like substances, it may occasionally cause:
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Nausea or vomiting
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Headache
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Heartburn or epigastric pain
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Insomnia or irritability
2026 Safety Update: While Brezofil has a superior safety profile, patients with pre-existing heart conditions should be monitored for palpitations. Research published in the Journal of Clinical Medicine indicates that Doxofylline shows significantly fewer gastrointestinal and cardiac side effects than traditional theophylline therapies.
Important Warnings & Precautions
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Drug Interactions: Avoid taking with other xanthine derivatives. Use caution with erythromycin, allopurinol, and cimetidine as they can increase drug levels in the blood.
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Heart Health: Contraindicated in cases of acute myocardial infarction (heart attack) and low blood pressure (hypotension).
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Dietary Note: Limit high-caffeine intake (coffee, chocolate) while on this medication to avoid increased side effects.
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Pregnancy/Breastfeeding: Use during pregnancy only if clearly needed. It is generally contraindicated for nursing mothers as it can pass into breast milk.
Brezofil 200 vs. Monas 10: Key Differences and Usage
While both treat asthma, Brezofil is a bronchodilator that physically relaxes airway muscles, whereas Monas (Montelukast) is an anti-inflammatory that blocks chemical triggers (leukotrienes).
| Feature | Brezofil 200 (Doxofylline) | Monas 10 (Montelukast) |
| Drug Class | Methylxanthine / Bronchodilator | Leukotriene Receptor Antagonist |
| Primary Use | Asthma, COPD & Chronic Bronchitis | Asthma Prevention & Allergic Rhinitis |
| Mechanism | Relaxes Bronchial Smooth Muscle | Blocks Inflammatory Chemicals |
| Common Dosage | 2–3 Times Daily | Once Daily (Evening) |
| Unit Price | ৳8.00 | ৳17.50 |
Brezofil 200 Price in Bangladesh (January 2026 Update)
The following pricing reflects the current retail market rates for Incepta’s Brezofil range.
| Product Name | Strength | Unit Price (BDT) | Strip Price (10 Tablets) |
| Brezofil 200 | 200 mg | ৳8.00 | ৳80.00 |
| Brezofil 400 | 400 mg | ৳10.00 | ৳100.00 |
| Brezofil SR | 400 mg | ৳12.00 | ৳120.00 |
Brezofil 200 Alternative Brands & Prices
If you are looking for an alternative to Brezofil 200, here are the top 10 alternative brands in Bangladesh as of January 2026:
| Brand Name | Company Name | Price per Unit (BDT) |
| Docopa 200 | Aristopharma Ltd. | ৳8.00 |
| Dophylin 200 | ACME Laboratories Ltd. | ৳8.00 |
| Doxiva 200 | Nipro JMI Pharma | ৳8.00 |
| Flindof 200 | Square Pharmaceuticals | ৳7.50 |
| Fixolin 200 | Beximco Pharmaceuticals | ৳8.00 |
| Fylox 200 | Radiant Pharmaceuticals | ৳8.00 |
| Axofyl 200 | Orion Pharma Ltd. | ৳7.00 |
| Pulmodox 200 | UniMed UniHealth | ৳8.00 |
| Ventofil 200 | Eskayef (SK+F) | ৳6.00 |
| Doxorin 200 | Opsonin Pharma | ৳6.00 |
Frequently Asked Questions (FAQ) About Brezofil 200
Q: What is the Brezofil 200 mg price in Bangladesh?
As of January 2026, the retail price is ৳8.00 per tablet. A 10-tablet strip typically costs ৳80.00.
Q: What is Brezofil 200 used for?
It is used for the maintenance treatment of bronchial asthma, COPD, and other lung diseases where airway constriction (bronchospasm) occurs.
Q: What are the Brezofil 200 side effects?
Common side effects include nausea, headache, stomach upset, and occasionally insomnia. It is generally safer for the heart than older asthma tablets.
Q: Is Brezofil 200 safe during pregnancy?
It should be used only if clearly needed and prescribed by a doctor, as human data is limited. You can check the NCBI Bookshelf for general xanthine safety.
Q: What is the recommended Brezofil 200 dose?
For most adults and children over 12, the standard dose is one 200 mg tablet taken 2 to 3 times daily.
Q: Is Brezofil 200 a steroid?
No, Brezofil 200 is a bronchodilator (methylxanthine derivative), not a steroid.
Q: Can I take Brezofil 200 for a sudden asthma attack?
No, it does not work fast enough for emergencies. Always use a “blue” rescue inhaler (Salbutamol) for sudden shortness of breath.
Q: Does Brezofil 200 cause heart palpitations?
While much less likely than with theophylline, it can occasionally cause palpitations in sensitive individuals or at high doses.
Q: Are there any alternatives to Brezofil 200 in Bangladesh?
Yes, high-quality alternatives include Docopa 200, Dophylin 200, and Flindof 200, with prices ranging from ৳6.00 to ৳8.00.
Disclaimer: This is educational information only (updated January 2026). Not a substitute for professional medical advice. Always consult a qualified physician before starting/stopping any medication.
