Penvik DS is a prescription antibiotic containing Phenoxymethylpenicillin (also known as Penicillin V). It is a narrow-spectrum antibiotic belonging to the penicillin group, primarily used to treat mild to moderately severe infections caused by penicillin-sensitive microorganisms. It works by inhibiting the synthesis of the bacterial cell wall, leading to the death of the bacteria. Produced by Square Pharmaceuticals PLC, this guide provides the latest updates for February 2026.
What is Penvik DS Used For?
Penvik DS is primarily indicated for the treatment of:
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Respiratory Tract Infections: Including tonsillitis, pharyngitis, and laryngitis caused by streptococci.
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Skin and Soft Tissue Infections: Such as erysipelas and cellulitis.
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Scarlet Fever: Treatment and management of symptoms.
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Prophylaxis: Prevention of rheumatic fever recurrence and bacterial endocarditis in patients with congenital heart disease undergoing minor surgery (like dental extractions).
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Ear Infections: Management of otitis media in specific sensitive cases.
Critical Safety Note: Penvik DS should only be used for bacterial infections. It is ineffective against viral infections like the common cold or influenza. For detailed molecular data, you can review Penicillin V on DrugBank.
Dosage
The dosage of Penvik DS is determined by the severity of the infection and the patient’s age/weight. Standard adult protocols include:
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Standard Adult Dose: 250 mg to 500 mg every 6 hours, depending on the severity of the infection.
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Streptococcal Infections: 250 mg to 500 mg every 6 to 8 hours for 10 days.
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Rheumatic Fever Prophylaxis: 250 mg twice daily on a long-term basis.
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Administration: For maximum absorption, Penvik DS should be taken on an empty stomach, at least 1 hour before or 2 hours after meals.
Common Side Effects
While generally safe for those not allergic to penicillin, common side effects may include:
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Nausea and vomiting
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Diarrhea (mild)
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Epigastric distress (stomach ache)
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Oral thrush (long-term use)
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Black hairy tongue (rare)
Important Warnings & Precautions
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Allergy Warning: Do not use if you have a known allergy to Penicillins or Cephalosporins. Seek immediate emergency care if you experience swelling of the face, difficulty breathing, or hives.
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Complete the Course: Always finish the entire prescribed bottle, even if symptoms disappear, to prevent antibiotic resistance.
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Kidney Function: Use with caution in patients with significant renal impairment; dose adjustments may be necessary.
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Diarrhea: If severe, watery, or bloody diarrhea occurs, stop the medicine and contact a doctor immediately, as this may indicate a serious colon infection.
Penvik DS vs. Seclo: Key Differences
It is important to distinguish between antibiotics (like Penvik) and gastric acid reducers (like Seclo), as they are often used together but serve different purposes.
| Feature | Penvik DS (Penicillin V) | Seclo (Omeprazole) |
| Drug Class | Narrow-spectrum Antibiotic | Proton Pump Inhibitor (PPI) |
| Primary Use | Bacterial Infections (Throat/Skin) | Acidity, Heartburn, Ulcers |
| Action | Kills bacteria | Reduces stomach acid |
| Timing | Empty stomach (for absorption) | Before meals (usually morning) |
| Unit Price | ৳4.00 – ৳6.00 | ৳5.00 – ৳7.00 |
Penvik DS Price (February 2026 Update)
The following retail prices are current for Penvik variants produced by Square Pharmaceuticals PLC.
| Product Name | Strength | Unit Price (BDT) | Pack Size |
| Penvik DS Tablet | 500 mg (8 Lac IU) | ৳6.00 | 10 Tablets (Strip) |
| Penvik 250 Tablet | 250 mg (4 Lac IU) | ৳3.50 | 10 Tablets (Strip) |
| Penvik DS Syrup | 250 mg / 5 ml | ৳85.00 | 100 ml Bottle |
Penvik DS Alternative Brands & Prices
Phenoxymethylpenicillin is available under a few trusted brand names in Bangladesh for 2026
| Brand Name | Company Name | Price per Unit (BDT) |
| Oracyn-K 500 | Synovia Pharma (Sanofi) | ৳5.50 |
| Open 500 | Opsonin Pharma Ltd. | ৳5.50 |
| Pencit-V 500 | Aristopharma Ltd. | ৳5.50 |
| Oracyn-K 250 | Synovia Pharma (Sanofi) | ৳2.80 |
| Open 250 | Opsonin Pharma Ltd. | ৳2.80 |
| Biopen VK 250 | Biopharma Limited | ৳2.80 |
| Cytapen-V 250 | Edruc Limited | ৳2.30 |
| Pentab 250 | Sonear Laboratories Ltd. | ৳2.29 |
| G-Penicillin V 250 | Gonoshasthaya Pharma | ৳2.28 |
| Pharmapen 250 | Pharmadesh Laboratories | ৳2.20 |
Frequently Asked Questions (FAQ) About Penvik DS
Q: What is the Penvik DS price in Bangladesh?
As of February 2026, the retail price for Penvik DS 500 mg is ৳6.00 per tablet. The 100ml dry syrup bottle typically costs ৳85.00.
Q: What is Penvik DS used for?
It is used to treat bacterial infections of the throat (tonsillitis), lungs, and skin. It is also frequently used to prevent the recurrence of rheumatic fever.
Q: What are the common Penvik DS side effects?
Common side effects include stomach upset, nausea, and mild diarrhea. More serious but rare side effects include severe allergic reactions (skin rash or breathing trouble).
Q: Is Penvik DS safe during pregnancy?
Penicillins are generally considered safe during pregnancy (Category B). However, it should only be used if clearly needed and prescribed by a physician.
Q: Can I take Penvik DS for a viral flu?
No. Penvik DS is an antibiotic that only kills bacteria. It will not work against viruses that cause the common cold, flu, or most sore throats.
Q: Why should I take Penvik DS on an empty stomach?
Food can interfere with how the body absorbs this specific type of penicillin. Taking it 1 hour before or 2 hours after food ensures the medicine reaches maximum strength in your blood.
Q: What should I do if I develop a rash while taking Penvik DS?
Stop the medication immediately and consult a doctor. A rash can be a sign of a penicillin allergy, which can become dangerous if you continue taking the drug.
Q: Can children take Penvik DS?
Yes, but the dose is usually based on weight. The syrup form (Penvik DS Dry Syrup) is commonly used for children to ensure accurate dosing and easier swallowing.
Q: Does Penvik DS interact with birth control?
Some antibiotics can slightly decrease the effectiveness of oral contraceptives. It is advisable to use a barrier method (like a condom) while taking the antibiotic course.
Disclaimer: This is educational information only (updated February 2026). Not a substitute for professional medical advice. Always consult a qualified physician before starting/stopping any medication.
