Giane 35 is a combined hormonal preparation containing Cyproterone Acetate (2 mg) and Ethinylestradiol (0.035 mg). It is primarily used to treat women with severe acne, hirsutism (excessive hair growth), and symptoms associated with Polycystic Ovary Syndrome (PCOS). Produced by Renata Limited, it serves as both a dermatological treatment and an oral contraceptive when used correctly.
What is Giane 35 Used For?
Giane 35 is prescribed mainly for the following conditions in women:
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PCOS Management: Treatment of symptoms like irregular periods and hormonal imbalances.
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Severe Acne: Addressing acne that has not responded to oral antibiotics or other topical therapies.
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Hirsutism: Reduction of unwanted excessive hair growth on the face and body.
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Androgenization: Relief from other signs of male hormone dominance, such as seborrhea (very oily skin).
Clinical Insight: Giane 35 works by blocking the overproduction of androgens and reducing their levels in the blood. While it acts as a contraceptive, it should not be taken solely for birth control unless the patient also requires treatment for the androgen-dependent conditions mentioned above. For more technical data, you can review its profile on DrugBank.
Dosage
For most conditions, the cycle consists of one tablet daily for 21 consecutive days, followed by a 7-day tablet-free interval.
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Starting the Pack: The first tablet should be taken on the 1st day of the menstrual cycle.
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Administration: It is highly recommended to take the tablet at the same time each day (usually in the evening) to maintain consistent hormone levels.
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Continuation: After the 7-day break, start the next pack even if withdrawal bleeding has not finished.
Common Side Effects
Giane 35 is generally well-tolerated, but hormonal shifts may cause:
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Nausea or stomach pain
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Headache or migraine
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Breast pain or tenderness
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Weight changes (often due to fluid retention)
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Mood changes or feeling low
2026 Safety Update: According to recent data in the Journal of Women’s Health, users of combined hormonal pills have a slightly increased risk of venous thromboembolism (blood clots). Seek immediate medical attention if you experience unexplained swelling in the legs, chest pain, or sudden vision changes.
Important Warnings & Precautions
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Smoking & Age: Women over 35 who smoke have a significantly higher risk of serious cardiovascular side effects.
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Liver Health: Contraindicated in patients with active liver disease or liver tumors.
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Blood Clots: Avoid use if you have a history of deep vein thrombosis (DVT) or pulmonary embolism.
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Diabetes: Use with caution as it may affect glucose tolerance.
Giane 35 vs. Cleo 35: Key Differences and Usage
Giane 35 and Cleo 35 are bioequivalent, meaning they contain the same active ingredients in the same strengths. The choice between them usually comes down to brand availability and manufacturer preference.
| Feature | Giane 35 (Renata) | Cleo 35 (Nuvista) |
| Active Ingredients | Cyproterone + Ethinylestradiol | Cyproterone + Ethinylestradiol |
| Primary Use | PCOS, Acne, Hirsutism | PCOS, Acne, Hirsutism |
| Pack Size | 21 Tablets | 21 Tablets |
| Mechanism | Anti-androgenic Hormonal | Anti-androgenic Hormonal |
| Box Price (Approx) | ৳200.00 | ৳199.50 |
Giane 35 Price in Bangladesh (January 2026 Update)
The following table provides the updated retail pricing for Giane 35 by Renata Limited.
| Product Name | Format | Strength | Price (BDT) |
| Giane 35 | Tablet | 2 mg + 0.035 mg | ৳199.50 (21-Tab Box) |
| Giane 35 | Unit | Per Tablet | ৳9.50 |
Giane 35 Alternative Brands & Prices
Here are the top 10 alternative brands available in Bangladesh as of January 2026:
| Brand Name | Company Name | Price (21-Tab Box BDT) |
| Cleo 35 | Nuvista Pharma | ৳199.50 |
| Dyana | Healthcare Pharma | ৳210.00 |
| Ginette 35 | Cipla (Imported) | ৳450.00 – ৳500.00 |
| Diane 35 | Bayer (Imported) | ৳1,050.00 – ৳1,100.00 |
| Carpela | Eris Life Sciences | ৳420.00 |
| Krimson 35 | Sun Pharma | ৳440.00 |
| Elestra | Macleods Pharma | ৳380.00 |
| Carrol | Alembic Pharma | ৳410.00 |
| Herface | Torrent Pharma | ৳400.00 |
| Hersuit | Eskag Pharma | ৳390.00 |
Frequently Asked Questions (FAQ) About Giane 35
Q: What is the Giane 35 price in Bangladesh?
As of January 2026, the retail price for a box of 21 tablets is approximately ৳199.50.
Q: What is Giane 35 used for?
It is used to treat severe acne, excessive hair growth (hirsutism), and irregular periods caused by PCOS. It also provides contraception.
Q: What are the Giane 35 side effects?
Common side effects include nausea, breast tenderness, weight gain, headaches, and mood swings.
Q: Is Giane 35 safe during pregnancy?
No. Giane 35 is strictly contraindicated during pregnancy. If you suspect you are pregnant, stop taking it immediately and consult a doctor. You can find more details on PubMed.
Q: What is the recommended Giane 35 dose?
One tablet daily for 21 days, followed by a 7-day break. It must be taken in the order marked on the pack.
Q: Does Giane 35 help with weight loss?
Generally, it does not. In fact, many users report mild weight gain due to water retention or increased appetite.
Q: Can Giane 35 treat oily skin?
Yes, by blocking androgens, it significantly reduces sebum production, which helps clear oily skin and acne.
Q: Is Giane 35 high risk?
Like all hormonal pills, it carries a small risk of blood clots. It is considered high risk for women who smoke, are obese, or have a history of heart disease.
Q: Are there alternatives to Giane 35 in Bangladesh?
Yes, common alternatives include Cleo 35, Dyana, and the original brand Diane 35.
Disclaimer: This information is for educational purposes as of January 2026. Hormonal medications must only be taken under the supervision of a gynecologist or endocrinologist.
