Exium MUPS 20 is a prescription medication containing Esomeprazole Magnesium in a Multiple-Unit Pellet System (MUPS) formulation. Unlike traditional tablets, the MUPS technology allows for more consistent drug absorption and better acid control. Produced by Radiant Pharmaceuticals Ltd. (under license from AstraZeneca), it is a primary treatment for gastroesophageal reflux disease (GERD) and peptic ulcers.
What is Exium MUPS 20 Used For?
Exium MUPS 20 mg is formulated to address several acid-related conditions:
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GERD Management: Treatment of symptoms such as persistent heartburn and acid regurgitation.
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Erosive Esophagitis: Healing of the esophagus lining damaged by stomach acid and maintenance of that healing.
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Peptic Ulcer Disease: Treatment of gastric and duodenal ulcers, including those caused by NSAIDs.
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H. pylori Eradication: Used in triple therapy to eliminate bacteria linked to chronic ulcers.
Clinical Insight: MUPS technology ensures that the active ingredient is released uniformly in the small intestine, providing a more predictable clinical effect compared to standard capsules. Recent reviews on DrugBank highlight Esomeprazole’s superior efficacy in maintaining gastric pH above 4.0 for longer periods.
Dosage
For adults and adolescents, the standard dosage is one 20 mg tablet once daily, usually taken 1 hour before a meal.
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Administration: The tablet should be swallowed whole with liquid. It should not be chewed or crushed.
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Special Note: For those with swallowing difficulties, the tablet can be dispersed in non-carbonated water and consumed within 30 minutes.
Common Side Effects
Exium MUPS is generally well-tolerated, with side effects being typically mild and transient:
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Headache
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Abdominal pain or flatulence
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Diarrhea or constipation
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Nausea or dry mouth
2026 Safety Update: Long-term use of PPIs like Exium has been linked in recent research to a higher risk of bone fractures and magnesium deficiency. According to studies indexed by the Mayo Clinic, patients on long-term therapy should be monitored for bone density and mineral levels.
Important Warnings & Precautions
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Malignancy: Relief of symptoms does not preclude the presence of gastric malignancy; consult a doctor if symptoms persist.
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Liver Health: Dose adjustment is required for patients with severe hepatic impairment (maximum 20 mg daily).
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Kidney Health: Use with caution in patients with severe renal insufficiency.
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Interactions: May interfere with the absorption of drugs like Ketoconazole, Iron salts, and Digoxin.
Exium MUPS 20 vs. Sergel 20: Key Differences and Usage
While both contain the same generic (Esomeprazole), Exium utilizes MUPS technology, which some clinicians prefer for its absorption profile, whereas Sergel 20 is often available in capsule form.
| Feature | Exium MUPS 20 (Radiant) | Sergel 20 (Healthcare) |
| Technology | MUPS (Multiple-Unit Pellet) | Conventional Capsule/Tablet |
| Absorption | Consistent & Predictable | Standard PPI Profile |
| Primary Use | Severe GERD & Acid Control | General Acidity & Ulcers |
| Common Dosage | Once Daily (Empty Stomach) | Once or Twice Daily |
| Unit Price | ৳11.00 | ৳7.00 – ৳11.00 |
Exium MUPS 20 Price in Bangladesh (February 2026 Update)
The following table provides the updated pricing for the Exium range by Radiant Pharmaceuticals Ltd.
| Product Name | Strength | Unit Price (BDT) | Strip Price (10 Tablets) |
| Exium MUPS 20 | 20 mg | ৳11.00 | ৳110.00 |
| Exium MUPS 40 | 40 mg | ৳16.50 | ৳165.00 |
| Exium Capsule | 20 mg | ৳7.00 | ৳70.00 |
Exium MUPS 20 Alternative Brands & Prices
If you are looking for an alternative to Exium MUPS 20, here is a comparison of top alternative brands in Bangladesh:
| Brand Name | Company Name | Price per Unit (BDT) |
| Nexum MUPS 20 | Square Pharmaceuticals | ৳10.00 |
| Maxpro MUPS 20 | Renata Limited | ৳10.00 |
| Esonix M 20 | Incepta Pharmaceuticals | ৳10.00 |
| Remmo 20 | Beximco Pharmaceuticals | ৳10.00 |
| Sergel MUPS 20 | Healthcare Pharmaceuticals | ৳11.00 |
| Esoral MUPS 20 | Eskayef (SK+F) | ৳10.00 |
| Maxima MUPS 20 | ACME Laboratories | ৳10.00 |
| Esoprex MUPS 20 | Beacon Pharmaceuticals | ৳11.00 |
| Esotid MUPS 20 | Opsonin Pharma | ৳10.00 |
| Progut MUPS 20 | Popular Pharmaceuticals | ৳11.00 |
Frequently Asked Questions (FAQ) About Exium MUPS 20
Q: What is the Exium MUPS 20 mg price in Bangladesh?
As of early 2026, the retail price for Exium MUPS 20 is ৳11.00 per tablet. A strip of 10 tablets costs ৳110.00.
Q: What is Exium MUPS 20 used for?
It is used to treat acid reflux (GERD), heal erosive esophagitis, treat stomach/duodenal ulcers, and manage conditions like Zollinger-Ellison syndrome.
Q: What are the Exium MUPS 20 side effects?
Common side effects include headache, diarrhea, nausea, and abdominal pain. Long-term use may slightly increase the risk of bone fractures.
Q: Is Exium MUPS 20 safe during pregnancy?
Exium should be used during pregnancy only if clearly needed. While no high risk has been established, always consult your doctor. You can review safety data on NCBI PMC.
Q: What is the recommended Exium MUPS 20 dose?
The standard dose for adults is one 20 mg tablet once daily, taken 30–60 minutes before breakfast.
Q: Is Exium MUPS 20 good for a cough?
It can help if the cough is caused by “silent reflux” (LPR), where stomach acid irritates the throat. It does not treat coughs caused by colds or flu.
Q: Does Exium MUPS 20 make you sleepy?
No, Exium is not known to cause drowsiness. If you feel unusually sleepy, consult your physician.
Q: Is Esomeprazole (Exium) high risk?
It is very safe for short-term use. High risk is usually only associated with long-term use (years), which may lead to vitamin B12 or magnesium deficiency.
Q: Are there any alternatives to Exium MUPS 20 in Bangladesh?
Yes, high-quality alternatives include Nexum MUPS (Square), Maxpro MUPS (Renata), and Esonix M (Incepta), mostly priced at ৳10.00.
Disclaimer: This is educational information only (updated January 2026). Not a substitute for professional medical advice. Always consult a qualified physician before starting/stopping any medication.
