Avolac is a prescription oral solution containing Lactulose, a synthetic disaccharide that acts as a hyperosmolar laxative. It works by drawing water into the colon through osmosis, which softens the stool and stimulates bowel movement. Produced by Aristopharma Ltd., Avolac is a standard treatment for chronic constipation and is also utilized to reduce blood ammonia levels in patients with liver disease.
What is Avolac Syrup Used For?
Avolac (3.35 gm/5 ml) is primarily prescribed for:
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Chronic Constipation: Long-term management of infrequent or difficult bowel movements
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Hepatic Encephalopathy: Prevention and treatment of brain dysfunction caused by severe liver disease (by reducing ammonia absorption).
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Intestinal Flora Balance: Restoration of healthy gut bacteria, often following long-term antibiotic therapy.
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Portal-Systemic Encephalopathy: Managing high ammonia levels in patients with portal hypertension.
Clinical Insight: While Avolac is highly effective, it typically takes 24 to 48 hours to produce a noticeable effect. Peer-reviewed research in the Journal of Clinical Gastroenterology highlights lactulose as a first-line osmotic agent due to its high safety profile. For a detailed molecular overview, you can visit the pharmacology of Lactulose on DrugBank.
Dosage
Avolac should be taken once daily (preferably at breakfast) for constipation or as directed for liver conditions. It can be mixed with water or fruit juice to improve taste.
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Adults (Constipation): Initially 15–30 ml (3–6 teaspoons) daily; maintenance dose is 10–25 ml.
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Children (7–14 years): Initially 15 ml (3 teaspoons) daily; maintenance 10 ml.
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Children (1–6 years): 5–10 ml (1–2 teaspoons) daily.
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Infants (under 1 year): 5 ml (1 teaspoon) daily.
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Hepatic Encephalopathy: Adults may require 30–45 ml three to four times daily.
Common Side Effects
Avolac is generally well-tolerated, though some patients may experience:
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Flatulence (gas) and bloating
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Abdominal cramps or discomfort
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Nausea or vomiting
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Diarrhea (usually indicates the dose is too high)
2026 Safety Update: According to recent data from Mayo Clinic, prolonged use or excessive dosage can lead to electrolyte imbalances, particularly low potassium. Patients using Avolac for more than six months should have their electrolytes monitored by a physician.
Important Warnings & Precautions
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Galactose-Free Diet: Contraindicated for patients who require a galactose-free diet.
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Diabetes: Contains lactose and galactose; use with extreme caution and monitor blood sugar.
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Intestinal Obstruction: Do not use if a bowel blockage or perforation is suspected.
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Hydration: Always drink plenty of water (6–8 glasses a day) to help the medication work effectively.
Avolac vs. Osmolax: Key Differences and Usage
While both are popular lactulose brands in Bangladesh, they differ slightly in manufacturer and price points.
| Feature | Avolac (Lactulose) | Osmolax (Lactulose) |
| Drug Class | Osmotic Laxative | Osmotic Laxative |
| Primary Use | Constipation & Liver Health | Constipation & Liver Health |
| Manufacturer | Aristopharma Ltd. | Square Pharmaceuticals |
| Action Mechanism | Draws water into the bowel | Draws water into the bowel |
| Unit Price (100ml) | ৳200.00 | ৳160.00 |
Avolac Syrup Price in Bangladesh (January 2026 Update)
The following table provides the updated retail pricing for Avolac variants.
| Product Name | Format | Strength | Price (BDT) |
| Avolac 100ml | Syrup/Solution | 3.35 gm/5 ml | ৳200.00 |
| Avolac 200ml | Syrup/Solution | 3.35 gm/5 ml | ৳320.00 |
Avolac Syrup Alternative Brands & Prices
If you are looking for an alternative to Avolac, here are 10 top brands available in Bangladesh as of January 2026:
| Brand Name | Company Name | Price (100ml BDT) |
| Tulos | ACME Laboratories Ltd. | ৳140.00 |
| Osmolax | Square Pharmaceuticals | ৳160.00 |
| Inolac | Incepta Pharmaceuticals | ৳140.00 |
| Serelose | Beximco Pharmaceuticals | ৳130.00 |
| Laclose | Opsonin Pharma Ltd. | ৳120.37 |
| Ezylax | Orion Pharma Ltd. | ৳140.45 |
| Actilac | Healthcare Pharma | ৳140.00 |
| Sinalac | Ibn Sina Pharma | ৳140.00 |
| Tulac | Eskayef (SK+F) | ৳140.00 |
| Regulose | General Pharma | ৳180.00 |
Frequently Asked Questions (FAQ) About Avolac Syrup
Q: What is the Avolac syrup price in Bangladesh?
As of January 2026, the retail price for a 100 ml bottle is ৳200.00, while the 200 ml bottle costs ৳320.00.
Q: What is Avolac used for?
It is primarily used to treat chronic constipation and to prevent/treat hepatic encephalopathy (a brain condition caused by liver failure).
Q: What are the Avolac syrup side effects?
Common side effects include gas (flatulence), stomach cramps, and nausea. Excessive use can cause diarrhea and electrolyte loss.
Q: Is Avolac safe during pregnancy?
Yes, Avolac is generally considered safe during pregnancy (Category B) as it is not absorbed into the bloodstream. However, always consult your doctor first. More details can be found on the NHS Pregnancy Guide.
Q: How long does Avolac take to work?
It typically takes 24 to 48 hours to produce a bowel movement. It is not an immediate-action laxative.
Q: Can diabetics take Avolac?
It contains small amounts of sugar (lactose/galactose). While generally safe at normal doses, diabetics should consult their doctor for high-dose liver therapy.
Q: Does Avolac cause habit formation?
No, lactulose is not known to be habit-forming, unlike some stimulant laxatives.
Q: Is Avolac good for infants?
Yes, it is often prescribed for infant constipation, but the dosage must be strictly followed as per a pediatrician’s advice.
Q: What are the alternatives to Avolac in Bangladesh?
Popular alternatives include Tulos (ACME), Osmolax (Square), and Inolac (Incepta), which are often more affordable than Avolac.
Disclaimer: This is educational information only (updated January 2026). Not a substitute for professional medical advice. Always consult a qualified physician before starting any new treatment.
