Enterogermina is a leading probiotic medication containing spores of Bacillus clausii. It is primarily used to restore the balance of intestinal flora that may be disrupted by diarrhea or the use of antibiotics. As a polyantibiotic-resistant probiotic, it is uniquely capable of surviving the acidic environment of the stomach and reaching the intestines intact. Produced by Synovia Pharma PLC (formerly Sanofi Bangladesh Ltd.), it remains a gold standard in digestive care.
What is Enterogermina Used For?
Enterogermina is formulated as an oral suspension to address:
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Intestinal Dysbiosis: Restoration of gut bacteria balance after illness or poor diet.
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Antibiotic-Associated Diarrhea: Prevention and treatment of diarrhea caused by antibiotic therapy.
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Digestive Disorders: Management of chronic or acute diarrhea and gastrointestinal discomfort in both adults and children.
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Vitamin Support: Helping correct dysvitaminosis (imbalance in vitamin production/absorption) caused by flora changes.
Clinical Insight: Unlike many probiotics, Bacillus clausii spores are highly resilient. Research published in the Frontiers in Microbiology journal highlights their ability to stimulate the immune system and inhibit the growth of pathogenic bacteria. For a deeper clinical review of its mechanism, you can visit the pharmacology profile on DrugBank.
Dosage
Enterogermina is usually administered in 5ml mini bottles. The liquid is tasteless and can be taken directly or mixed with water, milk, or fruit juice.
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Adults: 2 to 3 mini bottles per day.
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Children & Infants: 1 to 2 mini bottles per day.
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Timing: Doses should be spaced regularly throughout the day. If taking alongside antibiotics, it should be administered in the interval between antibiotic doses.
Common Side Effects
Enterogermina is exceptionally well-tolerated across all age groups. Side effects are extremely rare but may occasionally include:
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Mild bloating
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Flatulence (gas)
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Skin rash or hypersensitivity (rare)
Important Warnings & Precautions
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Shake Before Use: Always shake the vial well before consumption to ensure the spores are properly suspended.
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Single Use: Once a vial is opened, it should be consumed immediately to avoid contamination.
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No Injection: This medication is for oral use only. It must never be injected.
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Antibiotic Gap: Ensure at least a 2-hour gap between taking an antibiotic and Enterogermina for maximum efficacy.
Enterogermina vs. Probio : Key Differences
Both Enterogermina and Probio are probiotics used to restore the natural balance of “good bacteria” in the gut, especially during or after a bout of diarrhea. However, they differ in the specific strains of bacteria they contain and their formulation.
| Feature | Enterogermina | Probio |
| Main Component | Bacillus clausii | Multistrain (e.g., L. acidophilus, B. longum, etc.) |
| Formulation | Ready-to-drink liquid (vials) | Capsules or Sachets |
| Storage | No refrigeration needed | Usually no refrigeration (shelf-stable) |
| Taste/Odore | Tasteless, odorless (like water) | Varies (Sachets may be flavored) |
| Primary Strength | Survival against antibiotics | Broad-spectrum gut health |
Enterogermina Price in Bangladesh (January 2026 Update)
The pricing for Enterogermina remains standardized across major pharmacies, though bulk purchases of strips may offer slight discounts.
| Product Name | Strength | Unit Price (BDT) | Strip Price (10 Vials) |
| Enterogermina | 2 Billion Spores/5 ml | ৳70.00 | ৳700.00 |
Enterogermina Alternative Brands & Prices
If you are looking for an alternative to Enterogermina, here is a detailed comparison of the top 10 alternative brands for Bacillus clausii or similar probiotics in Bangladesh as of January 2026.
| Brand Name | Company Name | Price per Unit (BDT) |
| Acteria | Radiant Pharmaceuticals | ৳45.00 |
| Gutwell | Nexora Corporation | ৳85.00 |
| Baciflora | MTM International | ৳65.00 |
| Amcogermina | Nexora Corporation | ৳86.00 |
| Progermila | Noor Worldwide Ltd. | ৳75.00 |
| Goodbac-3S | Aristopharma Ltd. | ৳45.00 |
| Probio | Square Pharmaceuticals | ৳40.00 |
| Prolacto | Drug International Ltd. | ৳16.00 |
| Proteria | Opsonin Pharma | ৳30.00 |
| Rebio | Ibn Sina Pharmaceuticals | ৳28.00 |
Frequently Asked Questions (FAQ) About Enterogermina
Q: What is the Enterogermina price in Bangladesh?
As of January 2026, the retail price is ৳70.00 per vial. A full pack of 10 vials costs ৳700.00.
Q: What is Enterogermina used for?
It is used to treat and prevent alterations in intestinal bacterial flora, diarrhea, and digestive upsets caused by antibiotic or chemotherapy treatments.
Q: What are the Enterogermina side effects?
It is generally side-effect-free. Rare reports include mild bloating or skin rashes in people with specific hypersensitivities.
Q: Is Enterogermina safe during pregnancy?
Yes, Bacillus clausii spores are considered safe for use during both pregnancy and breastfeeding, as they are not absorbed into the bloodstream. Safety data is regularly updated on the Mayo Clinic portal.
Q: Can I mix Enterogermina with hot drinks?
It is recommended to mix it with room-temperature or cold drinks (milk, tea, or juice). Avoid boiling liquids as high heat may damage the spores.
Q: How long should I take Enterogermina?
For acute diarrhea, it is often taken for 5–7 days. However, always follow the specific duration prescribed by your doctor.
Q: Does it need to be refrigerated?
No, Enterogermina is stable at room temperature (up to 30°C) and does not require refrigeration, making it convenient for travel.
Q: Is it suitable for infants?
Yes, it is widely prescribed by pediatricians for infants and children to manage “unhappy tummies” and diarrhea.
Q: Are there any alternatives to Enterogermina in Bangladesh?
Yes, several high-quality alternatives like Acteria, Gutwell, and Baciflora are available, with prices ranging from ৳16.00 to ৳86.00 depending on the formulation.
Disclaimer: This is educational information only (updated January 2026). Not a substitute for professional medical advice. Always consult a qualified physician before starting any medication.
